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Reliability guarantee framework for the Sichuan–Tibet Railway

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 480-491 doi: 10.1007/s42524-021-0170-4

Abstract: The pathway for its application on railway construction was developed in this study.

Keywords： Sichuan–Tibet Railway     operational efficiency     reliability guarantee     Nine-Connotation     implementationpathway    

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Low-temperature caproate production, microbial diversity, and metabolic pathway in xylose anaerobic fermentation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1637-9

Abstract:

● Converting xylose to caproate under a low temperature of 20 °C by MCF was verified.

Keywords： Xylose fermentation     Caproate     Low temperature     Bifidobacterium     FAB pathway     RBO pathway    

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FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 714-728 doi: 10.1007/s11684-022-0959-5

Abstract: FRMD6 interacts and colocalizes with mTOR and S6K, which are the key molecules of the mTOR signaling pathwayFurthermore, knocking out FRMD6 inhibits the activation of the mTOR signaling pathway in Frmd6our results show that FRMD6 contributes to lung cancer progression by activating the mTOR signaling pathway

Keywords： FRMD6     lung cancer     mTOR pathway    

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Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 157-162 doi: 10.1007/s11684-011-0128-8

Abstract: At present, clinical pathway has become one of the most important health care reform measures in manyIn this study, the authors introduced basic concepts and explored the application of the clinical pathwaySuch concepts provide examples and experiences, on which the application of clinical pathway in Chinese

Keywords： evidence-based medicine     clinical pathway     methodology     concept     technical difficulty    

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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract:

Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulation

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

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Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 637-650 doi: 10.1007/s11684-021-0864-3

Abstract: Further evidence suggested that the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway

Keywords： apigenin     aminoglycosides     ototoxicity     oxidative stress     Nrf2 signaling pathway    

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Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus

Xiaoxuan Zhu,Xinyi Zeng,Chao Sun,Shilin Chen

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 285-293 doi: 10.1007/s11684-014-0350-2

Abstract: Here we review the recent advances in the biosynthetic pathway of terpenoid indole alkaloids (TIAs) inSecologanin is derived from terpenoid (isoprenoid) biosynthetic pathway, while tryptamine is derivedfrom indole biosynthetic pathway.Although many genes and corresponding enzymes have been characterized in this pathway, our knowledgeon the whole TIA biosynthetic pathway still remains largely unknown up to date.

Keywords： Catharanthus roseus     terpenoidindole alkaloids     biosynthetic pathway     vinblastine     vincristine    

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Genetic evidence in planar cell polarity signaling pathway in human neural tube defects

Chunquan Cai, Ouyan Shi

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 68-78 doi: 10.1007/s11684-014-0308-4

Abstract: The planar cell polarity (PCP) pathway controls the process of convergent extension (CE) during gastrulationThis review summarizes the cumulative results of recent studies on PCP signaling pathway and human NTDs

Keywords： planar cell polarity     neural tube defects     rare mutations    

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Twenty years of achievements in China’s implementation of the Stockholm Convention

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 12, doi: 10.1007/s11783-022-1587-7

Abstract:

● China’s implementation of the SC was systematically studied.

Keywords： Stockholm Convention     Persistent organic pollutants     Compliance     Effectiveness    

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Understanding barriers to BIM implementation: Their impact across organizational levels in relation to

Sander SIEBELINK, Hans VOORDIJK, Maaike ENDEDIJK, Arjen ADRIAANSE

Frontiers of Engineering Management 2021, Volume 8, Issue 2,   Pages 236-257 doi: 10.1007/s42524-019-0088-2

Abstract: of a contracting firm contributes to understanding the barriers that organizations face during the implementationOur study provides insights on where to focus BIM implementation measures and how to enhance organizational

Keywords： building information modeling     implementation barriers     maturity     organizational levels    

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Overview and problems of BIM implementation in Japan

Takashi KANETA, Shuzo FURUSAKA, Nisi DENG

Frontiers of Engineering Management 2017, Volume 4, Issue 2,   Pages 146-155 doi: 10.15302/J-FEM-2017007

Abstract: This paper aims to overview Building Information Modeling (BIM) implementation and problems of BIM implementationFirst, BIM implementation guidelines and pilot projects are introduced.Then, some popular BIM software together with typical implementation cases are provided.BIM implementation in Japan is not always encouraged via a top-down consensus in architectural firms

Keywords： Building Information Modeling     general contractor     architect     drawing     procurement     project management    

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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 263-274 doi: 10.1007/s11684-022-0935-0

Abstract: of calcium ions (Ca2+) and the expression of key genes involved in the calcium signaling pathway

Keywords： melanoma     neuropilin and tolloid-like 2     Ca2+/CaMKII signaling pathway    

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Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway

Xiaoqing Li, Xinxin Li, Genbei Wang, Yan Xu, Yuanyuan Wang, Ruijia Hao, Xiaohui Ma

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 688-696 doi: 10.1007/s11684-018-0662-8

Abstract: an effective drug for T2DM by ameliorating insulin resistance and regulating the PI3K/Akt signaling pathway

Keywords： XKQ     type 2 diabetes mellitus     KKAy mice     PI3K/Akt pathway     diabetic liver disease    

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Wnt/β-catenin signaling pathway and its role in hepatocellular carcinoma

ZHANG Xufeng, YU Liang, LU Yi

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 216-228 doi: 10.1007/s11684-008-0042-x

Abstract: -catenin signaling pathway has been identified as a key cellular pathway in embryogenesis and diseaseobserved and their exact functions approached, thus ensuring the most complicated understanding of this pathwayIn hepatocellular carcinoma (HCC), with a deeply understanding of this pathway, more and more genes which-catenin signaling pathway has recently been identified and their exact roles in HCC pursued.In this review, we will focus on a mostly updated understanding of this pathway and its observed role

Keywords： interacting     complicated understanding     embryogenesis     activation     organism development    

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Thoughts on strategies and paths to achieve carbon peaking and carbon neutrality in China

Frontiers in Energy 2023, Volume 17, Issue 3,   Pages 324-331 doi: 10.1007/s11708-023-0883-7

Abstract: Next, eight major implementation paths for achieving the goals of “carbon peaking and carbon neutrality

Keywords： carbon peaking and carbon neutrality     strategy     implementation path     important sci-tech innovation implementation    

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Title Author Date Type Operation

Reliability guarantee framework for the Sichuan–Tibet Railway

Journal Article

Low-temperature caproate production, microbial diversity, and metabolic pathway in xylose anaerobic fermentation

Journal Article

FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression

Journal Article

Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine

Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Journal Article

Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus

Xiaoxuan Zhu,Xinyi Zeng,Chao Sun,Shilin Chen

Journal Article

Genetic evidence in planar cell polarity signaling pathway in human neural tube defects

Chunquan Cai, Ouyan Shi

Journal Article

Twenty years of achievements in China’s implementation of the Stockholm Convention

Journal Article

Understanding barriers to BIM implementation: Their impact across organizational levels in relation to

Sander SIEBELINK, Hans VOORDIJK, Maaike ENDEDIJK, Arjen ADRIAANSE

Journal Article

Overview and problems of BIM implementation in Japan

Takashi KANETA, Shuzo FURUSAKA, Nisi DENG

Journal Article

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Journal Article

Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway

Xiaoqing Li, Xinxin Li, Genbei Wang, Yan Xu, Yuanyuan Wang, Ruijia Hao, Xiaohui Ma

Journal Article

Wnt/β-catenin signaling pathway and its role in hepatocellular carcinoma

ZHANG Xufeng, YU Liang, LU Yi

Journal Article

Thoughts on strategies and paths to achieve carbon peaking and carbon neutrality in China

Journal Article